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These success, along with a earlier report exhibiting that a little-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like actions in mice,two assistance the strategy of concentrating on ACKR3 as a novel solution to modulate the opioid program, which could open up new therapeutic avenues for opioid-linked Ailments.Tabernaemontana divaricata Conolid